We will adapt the extensively validated MISCAN microsimulation models for the evaluation of breast, cervical and colorectal cancer screening to apply to Georgia, Romania and Montenegro, taking into account the background risk (incidence and mortality) of disease, demographics and country-specific information about key indicators and health services. Using the models, the long term outcomes of feasible options to improve the cancer screening programmes will be calculated. Participants of other countries will be enabled to use the web-based version of the MISCAN models to generate a country-specific model to use to construct their own road map and evaluation their screening programme. They will be trained in the use of this tool during the workshops organised by WP 8.